Non sedating second and third generation antihistamines

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Selective leukotriene receptor antagonist that inhibits the cysteinyl leukotriene (Cys LT 1) receptor.Selectively prevents action of leukotrienes released by mast cells and eosinophils.

non sedating second and third generation antihistamines-89

non sedating second and third generation antihistamines-21

non sedating second and third generation antihistamines-65

Only cetirizine causes drowsiness more frequently than placebo. Peak plasma levels reached within 1 h and half-life is about 8 h. Indicated for seasonal and perennial allergic rhinitis.They can be used prn, but adverse effects may limit their usefulness when taken on a daily basis.Some patients tolerate the adverse effects with prolonged use, but they may experience cognitive impairment, and driving skills may be affected.Induces also bronchial relaxation and increases heart rate and contractility by stimulating beta-adrenergic receptors.Fexofenadine is a nonsedating second-generation medication with fewer adverse effects than first-generation medications.

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